老年宫颈癌50例临床及预后分析

目的：探讨老年宫颈癌的临床病理特征及预后影响因素。方法：对50例老年宫颈癌患者的临床特点及生存情况进行回顾性分析。结果：鳞状细胞癌45例（90．0％），腺癌4例（8．0％），透明细胞癌1例（2．0％）；≤Ⅱa期占16．0％，≥Ⅱb期占84．0％；主要临床症状为绝经后不规则阴道流血，全组1、3、5年生存率分别为82．0％，66．0％，54．0％。多因素分析结果显示病理类型、临床分期及淋巴结转移情况是老年宫颈癌患者预后的独立影响因素（均P〈0．05）。结论：KPS评分≥70分、鳞癌、临床分期为Ⅰ期、Ⅱ期，无淋巴结转移的患者预后较好，病理类型、临床分期及淋巴结转移情况是老年宫颈癌患者预后的独立影响因素。

Clinical and Prognostic Analysis of 50 Elderly Patients with Cervical Cancer

Objective： To investigate the clinicopathologic features and prognostic factors of elderly patients with cervical cancer. Methods：We retrospectively analyzed the clinical characteristics and survival from 50 elderly patients with cervical cancer in our hospital from 2002 to 2007. Results： Squamous cell carcinoma in 45 cases （90.0%）, adenocarcinoma in 4 cases （8.0%）, clear cell carcinoma in 1 case （2.0%）; ≤Ⅱ a period accounted for 16.0%, ≥Ⅱ b for 84.0%; Irregular vaginal bleeding after menopause was the main clinical symptoms, the entire group survival rates of 1, 3, 5-year were 82.0%, 66.0% and 54.0% respectively. The multivariate analysis showed that pathological type, clinical stage and lymph node metastasis were independent prognostic risk factors （P 〈 0.05）. Conclusion：KPS score ≥ 70 points, squamous cell carcinoma, clinical stage Ⅰ,Ⅱ, and without lymph node metastasis of the patients have better prognosis. Pathological type, clinical stage and lymph node metastasis were independent prognostic factors in elderly patients with cervical cancer.