| Ghrelin发现和结构的研究现状 |
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| 引用本文： | 王丽晔,李峰,宋月晗,马佳美,李思耐,关冰河.Ghrelin发现和结构的研究现状[J].生物磁学,2011(18):3589-3591. |
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| 作者姓名： | 王丽晔 李峰 宋月晗 马佳美 李思耐 关冰河 |
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| 作者单位： | 北京中医药大学,北京100029 |
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| 基金项目： | 基金项目：北京中医药大学自主课题（52202） |
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| 摘 要： | Ghrelin是生长激素促分泌素受体（growth hormone secretagogue receptor，GHSR）的内源性配体，是1999年由Kojima等人从大鼠胃组织中发现的含28个氨基酸的多肽，主要由胃黏膜泌酸腺X／A样细胞分泌并通过与其特异性受体结合而产生多种生物学效应。本文总结了近几年的文章，旨在通过对Ghrelin的发现和结构的介绍，为以后的相关研究奠定基础。
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| 关 键 词： | Ghrelin 脑肠肽 结构 |
The discovery and structure of Ghrelin |
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| WANG Li-ye,LI Feng,SONG Yue-han,MA Jia-mei,LI Si-nai,Guan Bing-he.The discovery and structure of Ghrelin[J].Biomagnetism,2011(18):3589-3591. |
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| Authors: | WANG Li-ye LI Feng SONG Yue-han MA Jia-mei LI Si-nai Guan Bing-he |
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| Institution: | (Beijing, University of Chinese Medicine, 100029, Beijing, China) |
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| Abstract: | Ghrelin is the endogenic ligand of growth hormone secretagogue receptor （GHSR）, it was detected in stomach of mouse by Kojima in 1999 for the first time, it is a polypeptide which has 28 amino acids. Ghrelin is excreted by X/A cells in stomach mucous membrane secretory and do the deed through combing with its specificity antibody. The article summarizes many papers which appeard in recent years and wants to lay the foundation of correlational investigation. |
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| Keywords: | Ghrelin Braingut petide Structure |
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