青年妇女患宫颈癌的临床特点及预后分析

目的：探讨青年妇女患宫颈癌的临床特点并行预后分析。方法：选取2008年1月-2013年1月在我院接受治疗的青年妇女宫颈癌33例患者观察组，同期在我院接受治疗的大于35岁49例患者为对照组。对两组患者的发病相关因素及临床病理特征进行回顾性分析及对两组患者预后分析，随访患者5年内生存率及2年内复发率。结果：两组患者初次性行为差异无统计学意义（P〉0．05）；两组患者避孕方式与妊娠次数比较均有显著性差异（P〈0．05）；两组患者临床分期与宫颈形态无显著性差异（P〉0．05）；两组癌灶大小、病理分型、宫颈肌层浸润深度及盆腔淋巴转移具有显著性差异（P〈0．05）；观察组较对照组患者早期（Ⅰa—Ⅱa）与晚期（≥Ⅱb）的两年内复发率及五年生存率差异均有显著性差异（P〈0．05）。结论：青年妇女宫颈癌患者具有癌灶大、腺癌发病率高、宫颈肌层浸润深度≥1／2肌层和盆腔淋巴结转移阳性的临床特点。

The Prognosis Analysis and Clinical Characteristics of Young Women with Cervical Cancer

Objective： To investigate the prognostic analysis and Clinical Characteristics of young women with cervical cancer. Methods： We selected 33 ,young woman patients with cervical cancer who were treated during January, 2008 to January, 2013 in our hospital as observation group, and 49 patients whose ages were elder than 35 years old as control group. We analyzed the modality related factors and the clinical and pathological features in two groups of patients retrospectively. The prognosis of patients including 5-year survival rate and 2-year recurrence rate were followed up to analyze the prognosis of two groups. Results： There was no statistically difference in first sexual intercourse between two groups （P〉0.05）. There was significant difference in contraceptive method and number of pregnancy（P〈0.05）. There was significant difference in clinical stage and cervical morphology between two groups. There was significant difference in cancer size, pathological type, the invasion depth in cervical muscle layer, pelvic lymph node metastases between two groups（P〈0.05）. The 2-year recurrence and 5-year survival rate of early （Ⅰa-Ⅱ a） and late （≥ Ⅱ b） in observation group were significantly different from the control group（P〈0.05）. Conclusion： Young women with cervical cancer have the clinical features of large tumor size, high adenocarcinoma modality, cervical muscle layer invasion ≥ 1/2 muscle layer and pelvic lymph node metastasis.