Functional prediction of hypothetical proteins in human adenoviruses |
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Authors: | Shane Dorden Padmanabhan Mahadevan |
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Institution: | Department of Biology, University of Tampa, 401 W. Kennedy Blvd., Box 3F, Tampa, FL, 33606, USA |
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Abstract: | Assigning functional information to hypothetical proteins in virus genomes is crucial for gaining insight into their proteomes.
Human adenoviruses are medium sized viruses that cause a range of diseases. Their genomes possess proteins with
uncharacterized function known as hypothetical proteins. Using a wide range of protein function prediction servers, functional
information was obtained about these hypothetical proteins. A comparison of functional information obtained from these servers
revealed that some of them produced functional information, while others provided little functional information about these
human adenovirus hypothetical proteins. The PFP, ESG, PSIPRED, 3d2GO, and ProtFun servers produced the most functional
information regarding these hypothetical proteins. |
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Keywords: | Hypothetical protein human adenovirus pathogen protein function prediction web server |
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