| 抗冻蛋白结构与抗冻机制 |
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| 引用本文： | 谢秀杰,贾宗超,魏群.抗冻蛋白结构与抗冻机制[J].细胞生物学杂志,2005,27(1):5-8. |
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| 作者姓名： | 谢秀杰 贾宗超 魏群 |
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| 作者单位： | [1]北京师范大学生命科学学院，生物化学与分子生物学系，北京100875 [2]DepartmentofBiochemistry,Queen＇sUniversity,Kingston,OntarioK7L3N6,Canada |
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| 基金项目： | 海外香港青年学者合作基金资助项目(No.30228006)~~ |
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| 摘 要： | 抗冻蛋白(amifreeze proteins，AFPs)是20世纪60年代从极地鱼血淋巴中分离的一种大分子抗冻剂，迄今为止科学工作者已从陆地昆虫、植物、细菌和真菌等各类生物中分离到多种抗冻蛋白，并测得了它们的基因序列及一些晶体结构，近些年的工作主要集中在该类蛋白质抗冻机制的研究上。抗冻蛋白具有广泛的应用前景，它不但可以应用于食物的冷鲜贮存及移植器官的低温保存，还可通过转基因提高经济作物的抗冻能力。
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| 关 键 词： | 移植器官 AFP 低温保存 食物 机制 分离 基因序列 抗冻蛋白 昆虫 血淋巴 |
| 修稿时间： | 2004年6月8日 |
Antifreeze Protein Structure and Antifreeze Mechanism |
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| Xiu-Jie Xie,Zong-Chao Jia,Qun Wei.Antifreeze Protein Structure and Antifreeze Mechanism[J].Chinese Journal of Cell Biology,2005,27(1):5-8. |
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| Authors: | Xiu-Jie Xie Zong-Chao Jia Qun Wei |
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| Institution: | Xiu-Jie Xie,Zong-Chao Jia1,Qun Wei* |
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| Abstract: | Antifreeze proteins (AFPs) are macromolecular antifreeze first isolated from blood serum ofAntarctic Cod. Various AFPs have been found from insects, plants, bacteria and fungi and so on. Their genesequences and several crystal structures have been determined. Recent studies are focused on their antifreezemechanism in attempts to better understand how exactly AFPs work. AFPs have wide applications. They can aid inthe food storage and transplant organ cryopreservation, also by transgene they could enhance the antifreeze abilityof crops. |
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| Keywords: | antifreeze proteins crystal structure antifreezing mechanism transgene |
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