染色体浓缩素

染色体的形成是细胞周期的重要事件，然而有关染色体构筑动力学的分子机制仍未阐明。近年来对染色体浓缩素的分离与研究，为认识DNA浓缩和染色体构建机制提供了重要的线索，是细胞生物学研究领域的里程碑。现对浓缩素的发现过程，浓缩素在有丝分裂和减数分裂中的作用，浓缩素与黏着素的关系，浓缩素参与基因调节等方面进行综述，为相关领域的研究者提供参考。

Chromosome Condensin

Chromosome architecture is an important event in cell cycle. However, the molecular mechanisms in regulating chromosome construction dynamics are unclear. The recent studies on the chromosome condensin have provided new clues to further understand the mechanisms of chromosome architecture. Discovery of the chromosome condensin is believed to be a milestone in cell biology. In the present paper, the discovery history of condensin, its functions in mitosis and meiosis, relations with cohesin and roles in regulating gene expression are reviewed, which should be reference for the investigators in related fields.