| 真核翻译起始因子与肿瘤 |
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| 引用本文： | 魏群,曹江.真核翻译起始因子与肿瘤[J].细胞生物学杂志,2007,29(2):197-201. |
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| 作者姓名： | 魏群 曹江 |
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| 作者单位： | 浙江大学附属邵逸夫医院临床医学研究所 杭州310016 |
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| 摘 要： | 真核翻译起始因子(eukaryotic translation initiation factors,eIFs)是一类在蛋白质翻译起始的过程中发挥各自不同作用的蛋白质。近年来的研究发现,eIFs除了在蛋白质翻译起始中起作用外,还具有其他的作用,而且多种eIFs均与肿瘤的发生和进展相关。现就eIFs、eIFs与肿瘤的相关性及其在肿瘤治疗方面的应用等研究进展作一综述。
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| 关 键 词： | 真核翻译起始因子 表达 肿瘤 |
| 修稿时间： | 2006-07-31 |
Eukaryotic Translation Initiation Factors and Tumor |
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| Qun Wei,Jiang Cao.Eukaryotic Translation Initiation Factors and Tumor[J].Chinese Journal of Cell Biology,2007,29(2):197-201. |
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| Authors: | Qun Wei Jiang Cao |
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| Institution: | Clinical Research Institute, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, China |
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| Abstract: | Eukaryotic translation initiation factors (eIFs) are a group of proteins that plays different roles in the initiation steps of protein synthesis in eukaryotic cells. Recent studies showed that in addition to their transla-tion initiation roles, eIFs also play important roles in other processes such as tumor development and progression. This review focuses on recent achievements of eIFs research and their relationship with tumors. |
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| Keywords: | eukaryotic translation initiation factors expression tumor |
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