| 昆虫的NF-kB信号通路 |
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| 引用本文： | 卢新民,叶恭银.昆虫的NF-kB信号通路[J].细胞生物学杂志,2006,28(4):561-565. |
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| 作者姓名： | 卢新民 叶恭银 |
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| 作者单位： | 浙江大学应用昆虫研究所,杭州310029 |
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| 摘 要： | 昆虫NF-kB信号通路由toll和imd两条通路组成，通过转录因子NF-kB作用于靶标基因kB位点，而调节抗菌活性物质的表达。大量实验表明它能够被细菌、真菌和病毒的侵染所激活，在昆虫体液免疫中发挥着主要作用。现就昆虫的NF-kB信号通路的主要信号元件等进行综述。
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| 关 键 词： | NF-kB 昆虫 信号通路 信号元件 |
| 收稿时间： | 2005-07-18 |
| 修稿时间： | 2006-04-06 |
The NF-kB Signal Pathway of Insects |
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| Xin-Min Lu, Gong-Yin Ye.The NF-kB Signal Pathway of Insects[J].Chinese Journal of Cell Biology,2006,28(4):561-565. |
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| Authors: | Xin-Min Lu Gong-Yin Ye |
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| Institution: | Institute of Applied Entomology, Zhejiang University, Hangzhou 310029, China |
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| Abstract: | In insects, the NF-kB signal pathway, being composed of toll path and imd path, regulates the expression of antimicrobial genes as NF-kB factors binding kB sequence of targeted genes. Evidences have proved that this pathway plays a vital role in insect innate immunity, and can be triggered by proinflammatory microbes and viruses. In this article, the signal elements of this signal pathway in insects are reviewed mainly. |
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| Keywords: | NF-kB insects signal pathway signal elements |
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