Chiral counter-current chromatography: A survey of its instrument,mechanism, procedure,and applications |
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Authors: | Wen-Da Duan Xin-Yi Huang Duo-Long Di |
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Institution: | 1. CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, China
University of Chinese Academy of Sciences, Beijing, China;2. CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, China |
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Abstract: | The chiral separation by counter-current chromatography has made great progress in the past three decades. It has become increasingly popular in the field of chiral separation, and many applications have been introduced during the last years. This review mainly focuses on the current topics, applications, and trends in chiral separation by counter-current chromatography. It contains the development of modern counter-current chromatography apparatus, theory of counter-current chromatography, overview of applications of chiral counter-current chromatography enantioseparation, its current situation, and challenges. At last, some conclusions and perspectives also have been discussed in this review. |
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Keywords: | centrifugal partition chromatography chiral chromatography chiral separation counter-current chromatography high-speed counter-current chromatography |
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