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Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas
Institution:1. Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot 76100, Israel;2. Flow Cytometry Unit, Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot 76100, Israel;3. Department of Veterinary Resources, Weizmann Institute of Science, Rehovot 76100, Israel;4. Department of Pathology, Boston Children''s Hospital, Harvard Medical School, Boston, MA 02215, USA;5. Department of Pediatric Oncology, Dana-Farber Boston Children''s Cancer and Blood Disorders Center, Boston, MA 02215, USA;6. Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA;7. Racah Institute of Physics, Hebrew University, Jerusalem 91904, Israel
Abstract:
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  • Keywords:chromatin  epigenetic heterogeneity  single-cell  CyTOF  DIPG  H3-K27M  glioma  oncohistone  histone modifications  cancer heterogeneity
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