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A Conserved Noncoding Locus Regulates Random Monoallelic Xist Expression across a Topological Boundary
Institution:1. Mammalian Developmental Epigenetics Group, Genetics and Developmental Biology Unit, Institut Curie, PSL Research University, CNRS UMR3215, INSERM U934, Paris, France;2. Berlin Institute for Medical Systems Biology, Max Delbruck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany;3. Bioinformatics, Biostatistics, Epidemiology and Computational Systems Unit, Institut Curie, PSL Research University, INSERM U900, Paris, France;4. MINES ParisTech, PSL Research University, Centre for Computational Biology (CBIO), Paris, France;5. Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland;6. University of Basel, Basel, Switzerland;7. Transgenesis Facility, Institut Curie, Paris, France;8. Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie, Paris, France;9. Department of Developmental Biology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands;10. Department of Biology, Humboldt University, Berlin, Germany;11. Collège de France, Paris, France
Abstract:
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  • Keywords:TADs  X-inactivation  cis-regulatory landscape  gene regulation  noncoding RNA  silencer  enhancer  Xist  Linx  5C
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