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53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination
Institution:1. Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD 20892, USA;2. Department of Genetics, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA;3. Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA;4. Department of Cancer Genetics and Epigenetics, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA;5. Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Center, Madrid 28029, Spain;6. Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA
Abstract:
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  • Keywords:homologous recombination  shieldin  BRCA1  resection  cancer  aging  PARPi  53BP1
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