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FUS Regulates Activity of MicroRNA-Mediated Gene Silencing
Authors:Tao Zhang  Yen-Ching Wu  Patrick Mullane  Yon Ju Ji  Honghe Liu  Lu He  Amit Arora  Ho-Yon Hwang  Amelia F Alessi  Amirhossein G Niaki  Goran Periz  Lin Guo  Hejia Wang  Elad Elkayam  Leemor Joshua-Tor  Sua Myong  John K Kim  James Shorter  Jiou Wang
Institution:1. Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA;2. Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA;3. Department of Biology, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD 21218, USA;4. Department of Biophysics, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD 21218, USA;5. Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA;6. Keck Structural Biology Laboratory, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA;7. Department of Pharmacology, University of Washington, Seattle, WA 98195, USA;8. Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
Abstract:
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  • Keywords:microRNA  RNA  FUS  gene silencing  Argonaute  AGO2  ALS  FTD  neurodegeneration  Corresponding author
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