Adherence of Candida albicans to host cells |
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| Authors: | Michael L Pendrak Stephen A Klotz |
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| Institution: | Department of Research, Research Service, Veterans Affairs Medical Center, 4801 Linwood Blvd., Kansas City, MO 64128, USA; Department of Medicine, Veterans Affairs Medical Center, 4801 Linwood Blvd., Kansas City, MO 64128, USA; Departments of Medicine and Microbiology and Immunology, University of Kansas School of Medicine, Kansas City, KS, USA |
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| Abstract: | Abstract Research devoted to uncovering the mechanisms of adherence of Candida albicans to human tissue is reviewed. The physical aspects of adherence of the fungus to host cells and the biochemical and molecular features, as far as they are known, are discussed. Relevant pre- and post-adherence events in the pathogenesis of disease caused by this fungus are also noted. Putative adhesins and surface receptors of C. albicans for host proteins are discussed in detail. |
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| Keywords: | Candida albicans Candidiasis Adhesin Adherence |
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