首页 | 本学科首页   官方微博 | 高级检索  
   检索      

不同种类可吸收性外科缝线的体外降解性能评价
引用本文:陆华,孙皎,丁婷婷,顾国珍,罗忠富.不同种类可吸收性外科缝线的体外降解性能评价[J].上海生物医学工程,2008(4):239-241.
作者姓名:陆华  孙皎  丁婷婷  顾国珍  罗忠富
作者单位:上海交通大学医学院附属第九人民医院上海生物材料研究测试中心;中科院上海有机化学研究所;
基金项目:上海市重点学科(特色学科)建设项目资助(T0202)
摘    要:目的研究3种不同种类的可吸收性缝线的体外降解性能,分析其体外降解产物。方法将3种可吸收性缝线分别按比例浸入Sorensen缓冲液中进行体外降解实验,设3个降解周期组,每组设3个重复,分别过滤分离试样、碎片和溶液,计算试样的质量损耗率。并对其体外降解产物进行定性定量分析。结果3种试样体外降解的质量损耗率均逐期增大;不同种类缝线的体外降解液成分不同,且其主要成份含量逐期增加。结论:不同种类的可吸收性缝线应采用不同的定性定量分析方法,根据产物推断缝线的生物安全性。

关 键 词:可吸收缝线  体外  降解

Study on Degradability of the Absorbable Surgical Thread in vitro
LU Hua SUN Jiao DING Tingting GU Guozhen LUO Zhongfu .Ninth People's Hospital,College of Medicine,Shanghai Jiaotong University,Shanghai Biomaterials Research , Test Center,Shanghai.Study on Degradability of the Absorbable Surgical Thread in vitro[J].Shanghai Journal of Biomedical Engineering,2008(4):239-241.
Authors:LU Hua SUN Jiao DING Tingting GU Guozhen LUO Zhongfu Ninth People's Hospital  College of Medicine  Shanghai Jiaotong University  Shanghai Biomaterials Research  Test Center  Shanghai
Institution:LU Hua~1 SUN Jiao~1 DING Tingting~1 GU Guozhen LUO Zhongfu~2 1.Ninth People's Hospital,College of Medicine,Shanghai Jiaotong University,Shanghai Biomaterials Research , Test Center,Shanghai 200023 2.Shanghai Institute of Organic Chemical,Chinese Academy of Sciences
Abstract:Objective: To Study the degradability of there kinds of absorbable surgical threads in vitro, and analyze the products. Methods: The absorbable surgical threads were put into the Sorensen's cushion solution respectively in vitro. After 2w - 12w, the solutions were filtrated and the mass loss rates were calculated. Then analyzed the products from the solution. Results: The mass loss rate was increased every period. And the main product from the solution was different for every absorbable thread and its quantity was increased every period.Conclusion: The degradability in vitro can form a base of identification and quantification of degradability products from the different kinds of absorbable surgical threads. And it can be used to conclude the biological safety of the absorbable surgical threads.
Keywords:Absorbable surgical threads  in vitro  Degradability  
本文献已被 CNKI 维普 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号