pH regulation of calcium efflux by turtle liver mitochondria |
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Authors: | J A Arruda G Dytko |
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Institution: | Section of Nephrology, University of Illinois College of Medicine, Chicago 60612. |
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Abstract: | 1. Turtle liver mitochondria are capable of taking up calcium in a pattern similar to that described from rat liver mitochondria. 2. Turtle liver mitochondria also possess a system for calcium efflux which is extremely sensitive to changes in extramitochondrial pH. A decrease in extramitochondrial pH by addition of HCl or by gassing with CO2 caused a rapid release of calcium. 3. The profound changes in pH and pCO2 during deep diving likely affects Ca efflux from mitochondria in the turtle liver. |
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