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FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity
Authors:Yitzhak Reizel  Ashleigh Morgan  Long Gao  Jonathan Schug  Sarmistha Mukherjee  Meilín Fernández García  Greg Donahue  Joseph A Baur  Kenneth S Zaret  Klaus H Kaestner
Institution:1. Department of Genetics and Institute for Diabetes Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, 12-126 Smilow Center for Translational Research, 3400 Civic Center Boulevard, Philadelphia, PA 19104-5156, USA;2. Department of Physiology and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-5156, USA;3. Institute for Regenerative Medicine, Epigenetics Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-5156, USA
Abstract:
Keywords:DNA methylation  FoxA  tissue differentiation  enhancer activity  liver
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