| 贵州三都水族Y染色体单倍型频率分析 |
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| 引用本文： | 何燕,文波,单可人,黄薇,谢渊,吴昌学,熊晓燕,修瑾,张静,张小蕾,任锡麟,金力.贵州三都水族Y染色体单倍型频率分析[J].遗传,2003,25(3):249-252. |
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| 作者姓名： | 何燕 文波 单可人 黄薇 谢渊 吴昌学 熊晓燕 修瑾 张静 张小蕾 任锡麟 金力 |
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| 作者单位： | 1.贵阳医学院分子生物学重点实验室，贵州贵阳 550004；
2.复旦大学遗传学研究所，上海 200433；
3.国家人类基因组南方研究中心，上海 201203
1.The Key Lab of Molecular Biology,Guiyang Medical College,Guiyang Guizhou 550004,China;
2.Institute of Genetics,Fudan University,Shanghai 200433,China;
3.Chinese National Human Genome Center at Shanghai,Shanghai 201203,China |
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| 基金项目： | 贵州省省长专项基金项目(2001年度)，国家自然科学基金重大项目(39993420)资助 |
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| 摘 要： | 在92例贵州三都水族个体中，用PCR-RFLP法研究由11个单核苷酸多态位点(SNPs)组成的Y染色体单倍型频率分布，结果显示该人群的Y染色体主要为南方特异的H11和H9单倍型，两者频率高达90.22％。主成分分析结果显示其父系遗传结构与我国黎族、布依族等汉藏语系壮侗语族民族最为接近。通过Y染色体的遗传学观察与历史记载和语言学分类有较好一致性。
Abstract:Non-recombination region of Y-chromosome is a useful marker in tracing evolutionary history of paternal lineage.In the present study,total 92 individuals from Shui ethnic group in Sandu Shui Ethnic Group Autonomous County of Guizhou Province were inspected with 11 SNP sites including M7,M9,M15,M45,M89,M95,M119,M122,M130,M134 and YAP on Y-chromosome.All the subjects were required to be unrelated and without intermarriage with other ethnic groups within three generations.The haplotypes were analyzed by PCR-RFLP method.Four haplotypes H5,H8,H9 and H11 were detected with frequencies of 0.054,0.044,0.315 and 0.587,respectively.Principle component indicated that the paternal lineage of Shui ethnic group is much closer to Li ethnic group of Hainan Province and Bouyei ethnic group of Guizhou Province,which belong to the group of Zhuang-Dong branch of Sino-Tibetan language family.In addition genetic study of Shui coincides with its linguistic distribution.
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| 关 键 词： | Shui ethnic group Y-chromosome haplotype 基因频率 Key words Y染色体单倍型 水族 |
| 文章编号： | 0253-9772(2003)03-0249-04 |
| 修稿时间： | 2002年6月7日 |
The Distribution of Y-chromosome Haplotypes of Shui Ethnic in Sandu,Guizhou |
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| HE Yan ,WEN Bo ,SHAN Ke Ren ,HUANG Wei ,XIE Yuan ,WU Chang Xue ,XIONG Xiao Yan ,XIU Jin ,ZHANG Jing ,ZHANG Xiao Lei ,REN Xi Lin ,JIN Li.The Distribution of Y-chromosome Haplotypes of Shui Ethnic in Sandu,Guizhou[J].Hereditas,2003,25(3):249-252. |
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| Authors: | HE Yan WEN Bo SHAN Ke Ren HUANG Wei XIE Yuan WU Chang Xue XIONG Xiao Yan XIU Jin ZHANG Jing ZHANG Xiao Lei REN Xi Lin JIN Li |
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| Institution: | HE Yan 1,WEN Bo 2,SHAN Ke Ren 1,HUANG Wei 3,XIE Yuan 1,WU Chang Xue 1,XIONG Xiao Yan 3,XIU Jin 1,ZHANG Jing 3,ZHANG Xiao Lei 1,REN Xi Lin 1,JIN Li 2,3 |
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| Abstract: | Non recombination region of Y chromosome is a useful marker in tracing evolutionary history of paternal lineage.In the present study,total 92 individuals from Shui ethnic group in Sandu Shui Ethnic Group Autonomous County of Guizhou Province were inspected with 11 SNP sites including M7,M9,M15,M45,M89,M95,M119,M122,M130,M134 and YAP on Y chromosome.All the subjects were required to be unrelated and without intermarriage with other ethnic groups within three generations.The haplotypes were analyzed by PCR-RFLP method.Four haplotypes H5,H8,H9 and H11 were detected with frequencies of 0.054,0.044,0.315 and 0.587,respectively.Principle component indicated that the paternal lineage of Shui ethnic group is much closer to Li ethnic group of Hainan Province and Bouyei ethnic group of Guizhou Province,which belong to the group of Zhuang Dong branch of Sino Tibetan language family.In addition genetic study of Shui coincides with its linguistic distribution. |
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| Keywords: | Shui ethnic group Y chromosome haplotype allele frequency |
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