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贵州从江侗族Y-DNA及线粒体DNA 序列多态性分析
引用本文:齐晓岚,谢渊,单可人,褚迅,刘烜,李毅,赵艳,吴昌学,马骄,修瑾,任锡麟.贵州从江侗族Y-DNA及线粒体DNA 序列多态性分析[J].遗传,2005,27(1):30-34.
作者姓名:齐晓岚  谢渊  单可人  褚迅  刘烜  李毅  赵艳  吴昌学  马骄  修瑾  任锡麟
作者单位:贵阳医学院分子生物学重点实验室, 贵州贵阳 550004) Key Laboratory of Molecular Biology, Guiyang Medical College,Guiyang 550004, China)
摘    要:为分析贵州从江侗族父系及母系遗传结构,探讨其起源及迁徒, 通过聚合酶链式反应-限制性片段长度多态性(PCR-RFLP), 研究贵州从江侗族无亲缘关系个体由10个单核苷酸位点(SNPs)组成的Y染色体单倍型及11个单核苷酸位点组成的线粒体DNA单倍群频率。结果显示, 从40份男性样本的Y-SNP基因分型中,得到H6 、H11、H14 共3种单倍型;H11的频率为92.5%;通过对线粒体DNA基因分型,得到6种单倍群,有75%的个体能明确分类其所携带的单倍群特征,说明贵州从江侗族父系遗传构成相对简单。通过主成分分析,证明贵州从江侗族与其他的壮侗语族人群相聚,母系遗传结构复杂,无C单倍群分布可能为该民族特征之一。Abstract: To study the patrilineal and matrilineal genetic structure and the origin of Dong Ethnic of Congjiang Guizhou. Study the distribution of Y-chromosome haplotypes which consisted of 10 SNPs of Y-DNA and mtDNA haplogroups consisted of 11 SNPs by using PCR-RFLP method. The result is three haplotypes H6,H11,H14 were detected, the frequency of H11 is 92.5%. Six haplogroups were identified by mtDNA analysis, 75% of the people can be identified. The patrilineal genetic structure of Dong of Guizhou is simple, Principle component indicated that the structure is closer to Zhuang-Dong branch of Sino-Tibetan language family. The matrilineal genetic structure of Dong of Guizhou is complicated.

关 键 词:线粒体DNA单倍型  Key  words  Dong  ethnic  group  Y-chromosome  haplotype  Y染色体单倍型  贵州侗族  
文章编号:0253-9772(2005)01-0030-05
修稿时间:2003年12月31

The Sequence Polymorphism of Y-chromosome DNA and mtDNA of Dong Ethnic of Congjiang, Guizhou
QI Xiao-lan,XIE Yuan,SHAN Ke-ren,CHU Xun,LIU Xuan,LI Yi,ZHAO Yan,WU Chang-xue,MA Jiao,XIU Jin,REN Xi-lin.The Sequence Polymorphism of Y-chromosome DNA and mtDNA of Dong Ethnic of Congjiang, Guizhou[J].Hereditas,2005,27(1):30-34.
Authors:QI Xiao-lan  XIE Yuan  SHAN Ke-ren  CHU Xun  LIU Xuan  LI Yi  ZHAO Yan  WU Chang-xue  MA Jiao  XIU Jin  REN Xi-lin
Institution:Key Laboratory of Molecular Biology, Guiyang Medical College, Guiyang 550004, China. xiaolan76@163.com
Abstract:In order to explore the patrilineal and matrilineal genetic structure and the origin of Dong Ethnic of Congjiang in Guizhou province, the distribution of Y-chromosome haplotypes which consisted of 10 SNPs of Y-DNA and mtDNA haplogroups consisted of 11 SNPs were studied by using PCR-RFLP method.The result showed three haplotypes H6,H11,H14 were detected, the frequency of H11 is 92.5%.Six haplogroups were identified by mtDNA analysis, 75% of the people can be identified.The patrilineal genetic structure of Dong of Guizhou is simple, principle component indicated that the structure is closer to Zhuang-Dong branch of Sino-Tibetan language family.The matrilineal genetic structure of Dong of Guizhou is complicated.
Keywords:Dong ethnic group  Y-chromosome haplotype  mtDNA haplotype
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