| 大鼠部分肝切除前后热激处理对过氧化物酶基因表达的影响 |
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| 引用本文： | 徐存拴,张为民,王莹,赵绪永.大鼠部分肝切除前后热激处理对过氧化物酶基因表达的影响[J].遗传,2001,23(6):535-538. |
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| 作者姓名： | 徐存拴 张为民 王莹 赵绪永 |
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| 作者单位： | 1. 河南师范大学生命科学学院,
2. 暨南大学生命科学技术学院, |
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| 基金项目： | 河南省生物工程重点实验室资助项目(编号:PKL99002) |
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| 摘 要： | 用过氧化物酶原位复性电泳（SDS－POD－PAGE）技术分析了部分肝切除（partial hepatectomy,PH)、部分肝切除后再热激（partial hepatectomy following heat shock,PH-HS)和先热激再部分肝切除（heat shock following partial hepatectomy,HS-PH)后肝再生期间过氧化物酶（POD）基因表达差异，结果表明，PH中表达的POD基因种类（7个）＞PH－HS（5个）＞HS－PH（3个）；三个模型的POD总活性为：HS－PH＞PH－HS。根据实验结果推测，POD在肝再生和肝损伤恢复中起一定作用。
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| 关 键 词： | 部分肝切除 热激 过氧化物酶 等位酶 诱导酶 肝再生 基因表达 |
| 文章编号： | 0253-9772(2001)06-0535-04 |
| 修稿时间： | 2000年12月8日 |
Expression Difference of the Peroxidase Genes in Partial Hepatectomy and Heat Shock |
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| XU Cun-shuan ,ZHANG Wei-min ,WANG Ying ,ZHAO Xu-yong.Expression Difference of the Peroxidase Genes in Partial Hepatectomy and Heat Shock[J].Hereditas,2001,23(6):535-538. |
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| Authors: | XU Cun-shuan ZHANG Wei-min WANG Ying ZHAO Xu-yong |
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| Institution: | XU Cun-shuan 1,ZHANG Wei-min 1,WANG Ying 2,ZHAO Xu-yong 1 |
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| Abstract: | Expression difference of the peroxidase (POD) genes during liver regeneration after partial hepatectomy (PH), partial hepatectomy following heat shock (PH-HS) and heat shock following partial hepatectomy (HS-PH) was analyzed by POD renatured electrophoresis (SDS-POD-PAGE). The results showed that the expressed POD gene kinds in PH, PH-HS and HS-PH were 7, 5 and 3 respectively, and that the total activities of POD in the three models were HS-PH > PH > PH-HS. The results suggested that POD play some roles during liver regeneration and in recovery after liver damage. |
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| Keywords: | partial hepatectomy (PH) heat shock (HS) peroxidase (POD) allelic enzyme induced enzyme liver regeneration |
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