| MHC及其在种群遗传学和保护遗传学中的应用 |
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| 引用本文： | 杨光,陈旭衍,任文华,严洁.MHC及其在种群遗传学和保护遗传学中的应用[J].遗传,2002,24(6):712-714. |
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| 作者姓名： | 杨光 陈旭衍 任文华 严洁 |
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| 作者单位： | 南京师范大学生命科学学院遗传资源研究所，南京 210097 |
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| 基金项目： | 国家自然科学基金(39800014和30070116)，国家自然科学基金重大项目子课题(39899400)资助 |
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| 摘 要： | 主要组织相容性复合体（major histocompatibility complex,MHC）是脊椎动物体内与免疫应答调节密切相关的一个基因家族，是基因组中多态性最丰富的区域。通过MHC的遗传变异分析可以提供物种的遗传多样性水平、进化历史和种群动态，以及种群遗传结构等信息，并在濒危物种饲养繁殖种群的遗传管理中有重要应用。
MHC and Its Application in the Population and Conservation Genetics
YANG Guang,CHEN Xu-yan,REN Wen-hua,YAN Jie
Institute of Genetic Resources,Nanjing Normal University,Nanjing 210097,China
Abstract:The major histocompatibility complex (MHC),with the highest genetic polymorphism,is a cluster of genes involved in immune response regulation in the vertebrates.MHC can provide information such as population genetic diversity,evolutionary history and population dynamics,and population genetic structure etc.It can also be applied in the captive breeding programme for endangered vertebrate species.
Key words：major histocompatibility complex (MHC);genetic diversity,population viability;population genetic structure;captive breeding
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| 关 键 词： | 主要组织相容性复合体 遗传多样性 种群生存力 |
| 文章编号： | 0253-9772(2002)06-0712-03 |
| 修稿时间： | 2001年9月5日 |
MHC and Its Application in the Population and Conservation Genetics |
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| Guang Yang,Xu-yan Chen,Wen-hua Ren,Jie Yan.MHC and Its Application in the Population and Conservation Genetics[J].Hereditas,2002,24(6):712-714. |
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| Authors: | Guang Yang Xu-yan Chen Wen-hua Ren Jie Yan |
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| Institution: | Institute of Genetic Resources, Nanjing Normal University, Nanjing 210097, China. gyang@njnu.edu.cn |
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| Abstract: | The major histocompatibility complex (MHC),with the highest genetic polymorphism,is a cluster of genes involved in immune response regulation in the vertebrates.MHC can provide information such as population genetic diversity,evolutionary history and population dynamics,and population genetic structure etc.It can also be applied in the captive breeding programme for endangered vertebrate species. |
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| Keywords: | major histocompatibility complex (MHC) genetic diversity population viability population genetic structure captive breeding |
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