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关于组蛋白甲基化的研究
引用本文:李想,张飞雄.关于组蛋白甲基化的研究[J].遗传,2004,26(2):244-248.
作者姓名:李想  张飞雄
作者单位:首都师范大学生物系,100037 Department of Biology, Capital Normal University, Beijing China ,100037
摘    要:主要阐述了组蛋白甲基转移酶的类型,组蛋白H3中第9位赖氨酸甲基化与异染色质的形成、常染色体中基因表达的调控,以及与DNA甲基化之间的关系,说明了组蛋白甲基化与组蛋白乙酰化、磷酸化的相互关系, 指出组蛋白甲基化对维持细胞各种状态的平衡起到极其重要的作用。 Abstract: The types of histone methyltransferases, the relationship between methylation of Lysine 9 of H3 and the formation of heterochromatin, gene regulation in euchromatin, and that with DNA methylation, were mainly introduced. The interrelation between histone methylation and histone acetylation/phosphorylation was summarized. It is showed that histone methylation plays a very important role in maintaining the balance state of cell. The future research tendency of histone methylation was fantanstic.

关 键 词:组蛋白甲基化  组蛋白甲基转移酶  组蛋白磷酸化  组蛋白乙酰化  基因表达  Key  words  
文章编号:0253-9772(2004)02-0244-05
修稿时间:2003年3月10日

Research Progress of Histone Methylation
LI Xiang,ZHANG Fei-Xiong.Research Progress of Histone Methylation[J].Hereditas,2004,26(2):244-248.
Authors:LI Xiang  ZHANG Fei-Xiong
Institution:Department of Biology, Capital Normal University, Beijing 100 037, China.
Abstract:The types of histone methyltransferases, the relationship between methylation of Lysine 9 of H3 and the formation of heterochromatin, gene regulation in euchromatin, and that with DNA methylation, were mainly introduced. The interrelation between histone methylation and histone acetylation/phosphorylation was summarized. It is showed that histone methylation plays a very important role in maintaining the balance state of cell. The future research tendency of histone methylation was fantanstic.
Keywords:
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