| 中国人α珠蛋白基因3’HVR多态分布的研究 |
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| 引用本文： | 鲁晓宣,茅一萍,张军,李明发,高翼之,王世浚LU Xiao-Xuan,MAO Yi-Ping,ZHANG Jun,LI Ming-Fa,GAO Yi-Zhi,WANG Shi-Jun.中国人α珠蛋白基因3’HVR多态分布的研究[J].遗传,1995,17(3):13-15. |
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| 作者姓名： | 鲁晓宣 茅一萍 张军 李明发 高翼之 王世浚LU Xiao-Xuan MAO Yi-Ping ZHANG Jun LI Ming-Fa GAO Yi-Zhi WANG Shi-Jun |
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| 作者单位： | 南京铁道医学院生物学教研室, 南京 210009
Departmnet of Biology,Nanjing Railway Medical College,Nanjing 210009 |
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| 摘 要： | 本文以3’HVR为探针,对来自全国17省市的51名无血缘关系的健康人进行P vuⅡ限制性片段长度的多态分析,发现3’HVR在片段大小的变异范围及基因频率的分布均有中国人的特点。结果表明,纯合子占15.7%,杂合子占84 .3%,102个等位基因共有34个长度不同的等位片段,大小从2.0-7.0kb之间呈连续分布, 主要分布在2.0-2.5kb及4.0-6.0kb,频率分别为0.43和0.34。并与刘国仰、余裕炉等的资料进行综合比较,初步揭示了中国人群中3’HVR的多态特点。
Abstract: 51 unrelated Chinese individuals from 17 different provinces and cities were typed for PvuII restiction fragment length polymorphism with the probe 3’HVR.The frequencies of homozygotes and heterozygotes were estimated as 15.7% and 84.3%,34 distinguishable allele sizes showed a continue distribution from 2.0-7.0kb.The main alleles of 2.0-2.5kb and 4.0-6.0kb gave the gene frequencies of 0.43 and 0.34 respectively.The preliminary characteristics of 3’HVR locus in Chinese population were revealed.
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| 关 键 词： | 高变区序列 人α-珠蛋白基因簇 Key words 限制性片段长度多态性 Hyper variable region Restriction fragment length polymorphism 等位酶 独龙牛 遗传多样性 |
Restriction Fragment Length Polymorphism of alpha-Globin 3’HVR Locus in Chinese Population |
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| LU Xiao-Xuan,MAO Yi-Ping,ZHANG Jun,LI Ming-Fa,GAO Yi-Zhi,WANG Shi-Jun.Restriction Fragment Length Polymorphism of alpha-Globin 3’HVR Locus in Chinese Population[J].Hereditas,1995,17(3):13-15. |
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| Authors: | LU Xiao-Xuan MAO Yi-Ping ZHANG Jun LI Ming-Fa GAO Yi-Zhi WANG Shi-Jun |
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| Abstract: | |
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| Keywords: | Genetic diverity Allozyme Mithun(Bos frontalis) |
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