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广州汉族人群DYS19、DYS389Ⅰ/Ⅱ、DYS390多态性及其单体型
引用本文:唐双柏,郭景元,刘超,梁赏猷,王穗保TANG Shuang-bo,GUO Jing-yuan,LIU Chao,LIANG Shang-you,WANG Sui-bao.广州汉族人群DYS19、DYS389Ⅰ/Ⅱ、DYS390多态性及其单体型[J].遗传,2000,22(1):11-14.
作者姓名:唐双柏  郭景元  刘超  梁赏猷  王穗保TANG Shuang-bo  GUO Jing-yuan  LIU Chao  LIANG Shang-you  WANG Sui-bao
作者单位:1.中山医科大学法医系,广东广州 510089 2.广州市公安局刑事科学技术研究所,广东 广州 510030 1.Faculty of Forensic Medicine,Sun Yat?sen University of Medical Sciences,Guangzhou 510089 2.Institute of Criminal Sciences,Guangzhou 510030, China
摘    要:用PCR结合PAGE技术观察111例广州汉族男性DYS19、DYS389Ⅰ/Ⅱ、DYS390等位基因及单体型分布状况。结果显示:广州地区汉族男性DYS19基因座观察到5种等位基因,DYS389Ⅰ观察到4种等位基因,DYS389Ⅱ观察到5种等位基因,DYS390观察到5种等位基因;χ2检验表明上述各等位基因频率分布与其他地区人群存在明显的差异。此外,还观察到72种由上述基因座共同构成的单体型,单体型多样性达0.953。 Abstract: In order to apply a set of useful and high polymorphic Y?STRs in forensic practice and genetic analysis,we performed a population genetic study from Chinese.The allele distributions of the systems DYS19、DYS389Ⅰ/Ⅱ、and DYS390 were investigated in sample of 111 unrelated males from the area of Guangzhou, China.PCR products were detected using polyacrylamide gel electrophoresis and silver staining.5、4、5、5 alleles were observed in locus DYS19、DYS389Ⅰ、DYS389Ⅱ、DYS390 respectively.Different allele frequency distributions were observed when compared to other population.Haplotype frequency date of 72 different types were obtained.

关 键 词:Y染色体  短串联重复序列  遗传多态性  广州汉族人  Key  words  单体型  
修稿时间:1998-12-16

Y
Ladder.Y[J].Hereditas,2000,22(1):11-14.
Authors:Ladder
Abstract: In order to apply a set of useful and high polymorphic YSTRs in forensic practice and genetic analysis,we performed a population genetic study from Chinese.The allele distributions of the systems DYS19DYS389/Ⅱ、and DYS390 were investigated in sample of 111 unrelated males from the area of Guangzhou, China.PCR products were detected using polyacrylamide gel electrophoresis and silver staining.5455 alleles were observed in locus DYS19DYS389Ⅰ、DYS389Ⅱ、DYS390 respectively.Different allele frequency distributions were observed when compared to other population.Haplotype frequency date of 72 different types were obtained.
Keywords:
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