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生物钟基因研究新进展
引用本文:李经才,于多,王芳,何颖.生物钟基因研究新进展[J].遗传,2004,26(1):89-96.
作者姓名:李经才  于多  王芳  何颖
作者单位:沈阳药科大学时间生物学研究室,沈阳 110016 Chronobiology Laboratory,Shenyang Pharmaceutical University,Shenyang 110016,China
摘    要:生物钟基因普遍存在于生物界,其作用在于产生和控制昼夜节律的运转。生物钟基因及其编码的蛋白质组成反馈回路,维持振荡系统持续进行并与环境周期保持同步。各级进化水平物种生物钟的基因组成和控制途径有同有异。此文主要介绍蓝细菌、脉孢菌、果蝇、鼠和人昼夜钟的分子运作机制以及研究钟基因的意义和展望。 Abstract:The circadian clock genes,which generate and control the running of the circadian rhythms,exist in organisms ranging from prokaryotes to mammals.The oscillator genes and its coding proteins compose the feedback loops of circadian system.The kind,number and regulating route of clock genes are characterized by living things at different evolution levels.The molecular mechanism of the run of circadian clock genes in cyanobacteria,neurospore,fruit fly,mouse and human being is introduced in this article.

关 键 词:反馈回路  Key  words  circadian  rhythm  clock  genes  钟基因  昼夜节律  
文章编号:0253-9772(2004)01-0089-08
修稿时间:2002年12月2日

Advances in Studies of Biological Clock Gene
LI Jing-Cai,YU Duo,WANG Fang,HE Ying.Advances in Studies of Biological Clock Gene[J].Hereditas,2004,26(1):89-96.
Authors:LI Jing-Cai  YU Duo  WANG Fang  HE Ying
Institution:Chronobiology Laboratory, Shenyang Pharmaceutical University, Shenyang 110016, China. ljingcai2001@hotmail.com
Abstract:The circadian clock genes,which generate and control the running of the circadian rhythms,exist in organisms ranging from prokaryotes to mammals.The oscillator genes and its coding proteins compose the feedback loops of circadian system.The kind,number and regulating route of clock genes are characterized by living things at different evolution levels.The molecular mechanism of the run of circadian clock genes in cyanobacteria,neurospore,fruit fly,mouse and human being is introduced in this article.
Keywords:circadian rhythm  clock genes  feedback loop
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