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云南怒族STR基因座遗传多态性研究
引用本文:高树辉,王新淮,赖江华,郑海波,李生斌.云南怒族STR基因座遗传多态性研究[J].遗传,2002,24(2):125-130.
作者姓名:高树辉  王新淮  赖江华  郑海波  李生斌
作者单位:1.中国人民公安大学侦查系,北京 100038; 2.西安交通大学部级法医学重点实验室,西安 710061; 3.中国科学院遗传研究所人类基因组中心,北京 100101 1.China Peoples Public Security University,Beijing 100038,China; 2.National Laboratory of Forensic Sciences,Xian Jiaotong University,Xian 710061,China; 3.Human Genome Center &Beijing Genomics Institute,Institute of Genetics,Chinese Academy of Sciences,Beijing 100101,China
基金项目:国家自然科学基金 ( 396 70 399,392 0 0 14 1)资助项目
摘    要:本文选择9个STR基因座和Amelogenin基因座,利用基因测序,采用基因扫描技术,对云南怒族聚集地区84名无关个体血样进行研究,建立了云南怒族9个STR基因座的基因频率数据库。用χ2检验,9个STR基因座基因型分布符合Hardy-Weinberg平衡定律。与其他民族资料一样,本课题所获得的云南怒族9个STR基因座数据是一组有价值的DNA多态性遗传标记资料。为建立我国不同民族STR基因数据库提供了资料。 Abstract:In this study,blood samples were randomly drawn from 84 unrelated Nu individuals.The polymorphism of nine STR loci and Amelogenin locus were determined by DNA GeneScan.The genetic database on the distribution of gene frequency on the nine STR loci was established,statistical results showed that the genotype distributions were in agreement with Hardy-Weinberg equation.Compared with other population,the results in our study were of great value in human DNA genetic data instant method with the characteristics of precision and sensitivity.

关 键 词:STR  怒族  基因扫描  遗传多态性  Key  words  基因频率  
文章编号:0253-9772(2002)02-0125-06
修稿时间:2001年6月1日

Polymorphism of Nine STR Locus in Nu Population from Yunnan Province
GAO Shu-hui ,WANG Xin-huai ,LAI Jiang-hua ,ZHENG Hai-bo ,LI Sheng-bin.Polymorphism of Nine STR Locus in Nu Population from Yunnan Province[J].Hereditas,2002,24(2):125-130.
Authors:GAO Shu-hui  WANG Xin-huai  LAI Jiang-hua  ZHENG Hai-bo  LI Sheng-bin
Institution:China People's Public Security University, Beijing 100038, China. wanggaoshuhui@263.net
Abstract:In this study,blood samples were randomly drawn from 84 unrelated Nu individuals.The polymorphism of nine STR loci and Amelogenin locus were determined by DNA GeneScan.The genetic database on the distribution of gene frequency on the nine STR loci was established,statistical results showed that the genotype distributions were in agreement with Hardy-Weinberg equation.Compared with other population,the results in our study were of great value in human DNA genetic data instant method with the characteristics of precision and sensitivity.
Keywords:Nu population  STR  genescan  gene frequence  genetic polymorphism
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