| 不同猪种肠毒素大肠杆菌（ETEC）F4受体的微卫星标记遗传效应分析 |
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| 引用本文： | 刘鑫,施启顺,柳小春,蒋隽,黄生强.不同猪种肠毒素大肠杆菌（ETEC）F4受体的微卫星标记遗传效应分析[J].遗传,2006,28(8):945-948. |
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| 作者姓名： | 刘鑫 施启顺 柳小春 蒋隽 黄生强 |
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| 作者单位： | 湖南农业大学动物科技学院,长沙 410128 |
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| 基金项目： | 国家高技术研究发展计划(863计划) |
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| 摘 要： | 从猪13号染色体选取与E.coli F4受体基因连锁的4个微卫星座位研究中外猪种间的遗传差异性，并分析不同基因型与F4受体黏附表型的关系。结果表明，4个猪种在4个基因座均具有高度多态性，杂合度（H）在0.6117～0.7500之间，多态信息含量（PIC）达0.5749以上；同时中外猪种基因频率存在差异，微卫星座位连锁越紧密，差异性越大。微卫星S0222不同基因型间在沙子岭猪F4ab血清型黏附表型中差异显著；SW458座位AC基因型在沙子岭、大白两个品种中无黏附表型，可望作为对E.coliF4抗性基因的遗传标记。
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| 关 键 词： | 基因频率 遗传差异 ETEC 微卫星座位 |
| 文章编号： | 0253-9772(2006)08-0945-04 |
| 收稿时间： | 2005-11-17 |
| 修稿时间： | 2006-01-26 |
Analysis of Effect of Microsatellite Markers on Escherichia coli F4 (K88) Receptor in Different Swine Breeds |
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| LIU Xin,SHI Qi-Shun,LIU Xiao-Chun,JIANG Jun,HUANG Sheng-Qiang.Analysis of Effect of Microsatellite Markers on Escherichia coli F4 (K88) Receptor in Different Swine Breeds[J].Hereditas,2006,28(8):945-948. |
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| Authors: | LIU Xin SHI Qi-Shun LIU Xiao-Chun JIANG Jun HUANG Sheng-Qiang |
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| Institution: | College of Animal Science & Technology, Hunan Agricultural university, Changsha 410128, China |
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| Abstract: | Four microsatellite markers linked with Escherichia coli F4 receptor gene were selected from chromosome 13 of pig to analyze difference in hereditary between the genotype and F4 receptor adhesive appearance.Results showed that the microsatellite markers were highly polymorphic and the heterozygosities ranged from 0.6117 to 0.7500.The value of PIC was over 0.5749 and the heredity diversity of chinese pig breeds more higher than oversea's.On F4ab adhesive appearance of S0222,the difference among genotypes was significant in SZL breed.The AC genotype of SW458 had no adhesive appearance in SZL and LW breeds.Marker SW458 can thus be potentially used as a genetic marker for E.coli F4 resistive gene. |
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| Keywords: | ETEC |
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