| 动物线粒体核质基因互作的研究进展 |
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| 引用本文： | 赵兴波,吴常信,李宁.动物线粒体核质基因互作的研究进展[J].遗传,2001,23(1):81-85. |
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| 作者姓名： | 赵兴波 吴常信 李宁 |
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| 作者单位： | 1.中国农业大学动物科技学院，北京 100094;
2.中国农业大学农业生物技术国家重点实验室，北京 100094
1.Department of Animal Science and technology,China Agricultural University,Beijing 100094,P.R.China;
2.National Laboratories for Agrobiotechnology,China Agricultural University,Beijing 100094,P R.China |
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| 基金项目： | 国家重点基础研究发展规划项目(编号：G2000016100)和国家自然科子基金项目(30000119)资助 |
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| 摘 要： | 线粒体是重要的细胞器，为细胞的生命活动提供能量，线粒体的正常功能是核基因和线粒体基因共同作用维持的结果。线粒体DNA是动物细胞内唯一存在的核外遗传物质，线粒体DNA与核基因的相互作用维持着线粒体和线粒体内膜呼吸链氧化磷酸化的正常功能状态。本文就线粒体核质基因互作在人类疾病、衰老、细胞凋亡、氯霉素抗性、ANT、MnSOD、mtTFA的研究进展进行了综述。
Abstract：Mitochondria is the essential element for a cell,in which generates energy.The normal functions of a mitochondria are controlled by both mitochondrial genome and nuclear genome.Mitochondrial DNA is the only genome in the cytoplasmy of a cell,it encodes essential components of oxidative phosphorylation(OXPHOS)in mitochondrial inner membrane,generating cellular energy in the main form of adenosine triphosphate(ATP).In this paper,we reviewed the research development on interactions of nuclear and mitochondrial genes,including human disease and aging,apoptosis,chloromycetin resistance,ANT,MnSOD and mtTFA.
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| 关 键 词： | 线粒体 核质基因互作 mitochondrial 呼吸链氧化磷酸化 Keywords interaction of nuclear and cytoplasmy |
| 文章编号： | 0253-9772(2001)01-0081-05 |
| 修稿时间： | 2000年1月3日 |
Research Progress on Interaction Between Mitochondrial and Nucleus |
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| ZHAO Xing-bo,WU Chang-xin,LI Ning.Research Progress on Interaction Between Mitochondrial and Nucleus[J].Hereditas,2001,23(1):81-85. |
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| Authors: | ZHAO Xing-bo WU Chang-xin LI Ning |
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| Institution: | ZHAO Xing bo 1,LI Ning 2,WU Chang xin 1 |
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| Abstract: | Mitochondria is the essential element for a cell,in which generates energy.The normal functions of a mitochondria are controlled by both mitochondrial genome and nuclear genome.Mitochondrial DNA is the only genome in the cytoplasmy of a cell,it encodes essential components of oxidative phosphorylation(OXPHOS)in mitochondrial inner membrane,generating cellular energy in the main form of adenosine triphosphate(ATP).In this paper,we reviewed the research development on interactions of nuclear and mitochondrial genes,including human disease and aging,apoptosis,chloromycetin resistance,ANT,MnSOD and mtTFA. |
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| Keywords: | mitochondrial interaction of nuclear and cytoplasmy oxidative phosphorylation |
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