Production of monoclonal antibodies against mouse molar papilla cells |
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| Authors: | G Zidan J V Ruch |
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| Institution: | Institut de Biologie Médicale, Faculté de Médecine, Université Louis Pasteur, Strasbourg, France. |
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| Abstract: | To develop markers for the analysis of the molecular mechanisms of dental papilla cells differentiation, 10 monoclonal antibodies were produced against trypsin-isolated mouse molar dental papilla cells. These antibodies identify matrix components, cell membrane associated antigens and intracellular-constituents. Changes of the staining patterns were correlated with a typological hierarchy of dental papilla cells and with terminal differentiation of odontoblasts. |
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