| 胰岛素对蟾蜍卵母细胞膜电位及电解质的影响 |
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| 引用本文： | 李学斌,王文辉,成军,程治平.胰岛素对蟾蜍卵母细胞膜电位及电解质的影响[J].动物学报,1988(3). |
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| 作者姓名： | 李学斌 王文辉 成军 程治平 |
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| 作者单位： | 哈尔滨医科大学生理学教研室
(李学斌,王文辉,成军),哈尔滨医科大学生理学教研室(程治平) |
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| 摘 要： | 应用普通玻璃微电极和离子选择性微电极,对正常及经过胰岛素处理的中华大蟾蜍卵母细胞膜电位、细胞内Na~+、K~+、Cl~-、H~+等活度及膜对Na~+、K~+的转运系数进行了测定。结果表明,胰岛素在促进蟾蜍卵母细胞发育成熟同时,具有使膜电位降低、细胞内Na~+、Cl~-活度增加、K~+、H~+活度减少及K~+转运系数降低等作用。胰岛素的上述作用可能与膜的通透性改变及膜上钠泵活性和Na~+/H~+交换的改变有关。
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EFFECT OF INSULIN ON MEMBRANE POTENTIAL AND ELECTROLYTES IN TOAD OOCYTES |
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| LI XUEBIN WANG WENHUI CHENG JUN CHENG ZHIPING.EFFECT OF INSULIN ON MEMBRANE POTENTIAL AND ELECTROLYTES IN TOAD OOCYTES[J].Acta Zoologica Sinica,1988(3). |
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| Authors: | LI XUEBIN WANG WENHUI CHENG JUN CHENG ZHIPING |
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| Abstract: | Membrane potential, intracellular Na+, K+, Cl", H+ activities and Na+, K+ transference number in toad (Bufo bufo gargarizans) oocytes were measured in vitro by using conventional and ion-sensitive microelectrodes during the insulin-induced oocyte maturation. The results showed that the insulin-induced oocyte maturation was accompanied by the decreases in membrane potential, K+ transference number and intracellular K+ and H+ activities, and the increases in intracellular Na+ and Cl- activities. All above effects of insulin might be related to the changes of K+ permeability, N+/H+ exchange and the activity in membrane sodium pump. |
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| Keywords: | Insulin Ion-sensitive microelectrode Intracellular Na+ K* Cl- H+ acti-vities Na+/H+ exchange Toad oocyte |
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