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Lancea tibetica as the Tibetan herb: A review of its phytochemistry and pharmacology
Institution:1. Institute of Agro-Food Science and Technology, Shandong Academy of Agricultural Sciences, 202 Gongye North Road, Jinan 250100, PR China;2. Key Laboratory of Agro-Products Processing Technology of Shandong Province, Jinan 250100, PR China;3. Shaanxi University of Chinese Medicine, Shaanxi Collaborative Innovation Centre of Chinese Medicinal Resource Industrialization, Xianyang 712083, PR China;4. Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, Xianyang 712083, PR China;1. Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, PR China;2. School of Medicine and Life Sciences, University of Jinan, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, PR China;1. National Center for Pharmaceutical Crops, Arthur Temple College of Forestry and Agriculture, Stephen F. Austin State University, Nacogdoches, TX 75962-6109, USA;2. College of Life Science, Northeast Forestry University, 26 Hexing Road, Harbin, Heilongjiang 150040, China;1. Department of Pharmacy, Fujian University of Traditional Chinese Medicine, Qiuyang Road 1#, Fuzhou 350122, PR China;2. School of Pharmacy, Second Military Medical University, Guohe Road 325#, Shanghai 200433, PR China;3. Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Fengyang Road 415#, Shanghai 200003, PR China;4. School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Cailun Road 1200#, Shanghai 201203, PR China;1. Key Laboratory of Tropical Plant Resources and Sustainable Use, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Menglun 666303, PR China;2. University of Chinese Academy of Sciences, Beijing 100049, PR China
Abstract:This review, based on nearly 25 literary sources, discusses the chemical nature and biological effects of the whole plant of Lancea tibetica Hook. f. et Thoms (Scrophulariaceae). Several types of chemical constituents have been isolated from Lancea tibetica (LT) including 34 phenolpropanoids (16 lignans, 5 neolignans, 5 nonanones, 4 phenylpropanoid glycosides, and 4 propanediols), 9 flavones, 6 triterpenoids, and 11 amino acids. Various extracts and individual compounds derived from this species have been determined to possess a variety of pharmacological effects, such as anti-tumour and antioxidant functions. The results of data analysis on the chemical and pharmacological characteristics of LT support the view that this plant has many therapeutic properties, suggesting its potential as an effective herbal remedy. Finally, suggestions for further avenues of research on the chemical and pharmacological properties of LT and ways in which to further exploit LT are presented in this review.
Keywords:Phytochemistry  Biological effects
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