SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci |
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Authors: | Shi Yong Yong He Lin |
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Institution: | Bio-X Life Science Research Center, Shanghai Jiao Tong University, Shanghai, China. |
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Abstract: | In multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses oflinkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values with a large numberof samples has been sought for long. In order to achieve the goal of obtaining meaningful results directly from raw data,we developed a robust and user-friendly software platform with a series of tools for analysis in association study withhigh efficiency. The platform has been well evaluated by several sets of real data. |
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Keywords: | software linkage disequilibrium haplotype analysis genetic association study |
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