Signaling mechanisms for regulation of chemotaxis |
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Authors: | Wu Dianqing |
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Institution: | Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, CT 06030, USA. dwu@neuron.uchc.edu |
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Abstract: | Chemotaxis is a fascinating biological process, through which a cell migrates along a shallow chemoattractant gradient that is less than 5% difference between the anterior and posterior of the cell. Chemotaxis is composed of two independent, but interrelated processes-motility and directionality, both of which are regulated by extracellular stimuli, chemoattractants. In this mini-review, recent progresses in the understanding of the regulation of leukocyte chemotaxis by chemoattractant signaling are reviewed. |
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Keywords: | chemotaxis leukocyte signaling chemoattractant |
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