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G1 checkpoint is compromised in mouse ESCs due to functional uncoupling of p53-p21Waf1 signaling |
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| Authors: | Irina I Suvorova Bogdan B Grigorash Ilya A Chuykin Tatiana V Pospelova |
| Institution: | 1. Institute of Cytology, Russian Academy of Sciences, St-Petersburg, Russia;2. Saint-Petersburg State University, Saint-Petersburg State University, St-Petersburg, Russia;3. Mount Sinai School of Medicine, New York, NY, USA |
| Abstract: | |
| Keywords: | ATM/ATR signaling checkpoint control DNA damage HDAC inhibitors p53-p21/Waf1 pathway proteasomal degradation |