| 亚稀褶黑菇对小白鼠肝肾超微结构的影响 |
| |
| 引用本文： | 蒋盛岩,张志光,陈作红,张平.亚稀褶黑菇对小白鼠肝肾超微结构的影响[J].生命科学研究,2004,8(2):150-153. |
| |
| 作者姓名： | 蒋盛岩 张志光 陈作红 张平 |
| |
| 作者单位： | 1. 湖南师范大学,生命科学学院,中国湖南,长沙,410081;邵阳学院,生物工程系,中国湖南,邵阳,422004
2. 邵阳学院,生物工程系,中国湖南,邵阳,422004 |
| |
| 基金项目： | 湖南省自然科学基金(02JJY2057) |
| |
| 摘 要： | 对小白鼠用亚稀褶黑菇提取液进行毒性试验．测定了亚稀褶黑菇的半致死剂量LD50值；应用透射电镜观察了小白鼠亚稀褶黑菇中毒后的病理变化，结果表明．亚稀褶黑菇的LD50值为2852．1mg／kg，电镜检查发现。亚稀褶黑菇毒素主要损害肾脏，引起肾细胞核核膜肿胀．线粒体肿胀，溶酶体增多，肾细胞坏死．
|
| 关 键 词： | 亚稀褶黑菇 LD50值 超微结构 |
| 文章编号： | 1007-7847(2004)02-0150-04 |
| 修稿时间： | 2003年11月14 |
The Effects of Russula subnigricans Hongo on the Ultrastructure of Mouse Liver and Kidney Cells |
| |
| JIANG Sheng yan,ZHANG Zhi guang,CHEN Zuo hong,ZHANG Ping.The Effects of Russula subnigricans Hongo on the Ultrastructure of Mouse Liver and Kidney Cells[J].Life Science Research,2004,8(2):150-153. |
| |
| Authors: | JIANG Sheng yan ZHANG Zhi guang CHEN Zuo hong ZHANG Ping |
| |
| Institution: | JIANG Sheng yan1,2,ZHANG Zhi guang2,CHEN Zuo hong2,ZHANG Ping2 |
| |
| Abstract: | Toxicity tests in mice with the crude extracts of Russula subnigricans Hongo were carried out.The LD50 of the crude extracts of Russula subnigricans Hongo was determined.Transmission electron microscopy was used to observe the histopathologic changes in the poisoned mice.The result showed that the LD50 of the crude extracts of Russula subnigricans Hongo was 2 852.1 mg/kg.Electron microscopy analysis showed significant changes in kidney cells of the poisoned mice,including cell nuclear membrance swelling,mitochondrion cavity and kidney cell necrosis. |
| |
| Keywords: | Russula subnigricans Hongo LD_(50) ultrastructure |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
