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| 慢性疼痛患者静息态脑功能磁共振的默认网络研究 | |
| 引用本文： | 谢洪武,罗天友,陈日新,方维东,徐放明,宋云娥,吴飞,吕发金.慢性疼痛患者静息态脑功能磁共振的默认网络研究[J].生命科学研究,2011,15(6). |
| 作者姓名： | 谢洪武 罗天友 陈日新 方维东 徐放明 宋云娥 吴飞 吕发金 |
| 作者单位： | 1. 重庆医科大学中医药学院,中国重庆,400016 2. 重庆医科大学附属第一医院放射科,中国重庆40016 3. 江西中医学院附属医院针灸康复科,中国江西南昌,330006 |
| 基金项目： | 国家973项目(2009CB522902) |
| 摘 要： | 运用静息态功能磁共振成像技术(resting-state fMRI)研究慢性疼痛患者脑默认网络结构.通过选择双侧膝骨性关节炎(knee osteoarthritis,KOA)患者20例和正常志愿者20名,以后扣带回(posterior cingulated cortex,PCC)为种子点,分别进行fMRI扫描,分析配对两组受试者的脑功能连接情况.结果显示相对正常受试者,KOA患者存在异常脑功能连接,主要表现为PCC呈负激活,边缘叶、脑岛呈正激活. |
| 关 键 词： | 慢性疼痛 膝骨性关节炎 静息态功能磁共振成像 默认网络 |
Study of Default-mode Network in fMRI in Patients with Chronic Pain |
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| XIE Hong-wu , LUO Tian-you , CHEN Ri-xin , FANG Wei-dong , XU Fang-ming , SONG Yun-e , WU Fei , L Fa-jin.Study of Default-mode Network in fMRI in Patients with Chronic Pain[J].Life Science Research,2011,15(6). | |
| Authors: | XIE Hong-wu LUO Tian-you CHEN Ri-xin FANG Wei-dong XU Fang-ming SONG Yun-e WU Fei L Fa-jin |
| Institution: | XIE Hong-wu1,LUO Tian-you2,CHEN Ri-xin3,FANG Wei-dong2,XU Fang-ming1*,SONG Yun-e1,WU Fei2,LU Fa-jin2(1.School of Traditional Chinese Medicine,Chongqing Medical University,Chongqing 400016,China,2.Department of Radiology,The First Attached Hospital,3.Department of Acupuncture Recovery,Jiangxi Traditional Chinese Medicine College,Nanchang 330006,Jiangxi,China) |
| Abstract: | The resting-state functional magnetic resonance imaging(resting-state fMRI) was used to study the brain default network structure of chronic pain patients.In this study,20 patients who afflicted bilateral knee osteoarthritis(KOA) and 20 normal volunteers were selected.Based on seed region of posterior cingu-lated cortex(PCC) of default-mode network,fMRI scan was performed to analyze connection of brain function of the two groups.The results suggest that patients with KOA show abnormal brain functional conne... |
| Keywords: | constant pain knee osteoarthritis resting state functional magnetic resonance imaging default network |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |