| 新疆维吾尔族四个STR位点遗传多态性分析 |
| |
| 引用本文： | 袁俐,袁育康,冯继东,王红英,邢建新,李生斌.新疆维吾尔族四个STR位点遗传多态性分析[J].生命科学研究,2001,5(4):298-301. |
| |
| 作者姓名： | 袁俐 袁育康 冯继东 王红英 邢建新 李生斌 |
| |
| 作者单位： | 1. 石河子大学医学院免疫学教研室,
2. 西安交通大学医学院, |
| |
| 基金项目： | 国家自然科学基金资助项目(39970401) |
| |
| 摘 要： | 研究新疆维吾尔族人群D16S539、D13S317、D7S820和D5S818的STR基因位点的基因及基因型分布，获得4个基因座的群体遗传学数据。采用PCR扩增技术和基因扫描技术进行样本STR遗传结构分析，并与其他种族、人群的等位基因频率进行比较。结果表明4个基因位点在新疆维吾尔族人群中均具有遗传多态性。4个基因座的基因型分布均符合Hardy-Weinberg平衡定律（P＞0.05），不同人群基因频率分布存在一定的差异，所得到的等位基因频率等数据可为遗传学研究、法医个体畜产品识别及亲子鉴定提供依据。
|
| 关 键 词： | 短串联重复序列 基因扫描 遗传多态性 维吾尔族群体 STR位点 |
| 文章编号： | 1007-7847(2001)04-0298-04 |
| 修稿时间： | 2001年7月18日 |
Analysis on the Genetic Polymorphism of 4 STR Loci in Uygur in Xinjiang |
| |
| YUAN Li ,YUAN Yu kang ,FENG Ji dong ,WANG Hong ying ,XING Jian xing ,LI Sheng bin.Analysis on the Genetic Polymorphism of 4 STR Loci in Uygur in Xinjiang[J].Life Science Research,2001,5(4):298-301. |
| |
| Authors: | YUAN Li YUAN Yu kang FENG Ji dong WANG Hong ying XING Jian xing LI Sheng bin |
| |
| Institution: | YUAN Li 1,YUAN Yu kang 2,FENG Ji dong 3,WANG Hong ying 1,XING Jian xing 1,LI Sheng bin 2 |
| |
| Abstract: | The distribution of genes and genotypes of D16S539,D13S317,D7S820 and D5S818 were studied,and obtain genetics data in Xinjiang Uygur population. PCR technique and genescan technique were used to analyze the genetic structure of the 4 short tandem repeats(STR)loci. The allele frequencies were compared with other race or population data. The STR polymorphism at all of the 4 loci were observed in Xinjiang Uygur population. No deviation from Hard Weinberg equilibrium was observed. The allele distribution varies in different races and population. The data obtained can be used in population genetics investigation, individual identification and Paternity test. |
| |
| Keywords: | short tandem repeats(STR) genescan polymorphism Uygur population |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
