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Minocycline attenuates depressive-like behaviors in mice treated with the low dose of intracerebroventricular streptozotocin; the role of mitochondrial function and neuroinflammation
Authors:Mozafari  Haniyeh  Amiri  Shayan  Mehr  Shahram Ejtemaei  Momeny  Majid  Amini-khoei  Hossein  Bijani  Soroush  Hosseini  Mir-Jamal
Institution:1.Zanjan Applied Pharmacology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran
;2.Departments of Pharmacology and Toxicology, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, P. O. Box: 45139-56184, Iran
;3.Department of Human Anatomy and Cell Science, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada
;4.Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
;5.Hematology/Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
;6.Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran
;
Abstract:Molecular Biology Reports - Neuroinflammation and mitochondrial dysfunction are suggested as mechanisms which are implicated in the pathophysiology of depression. Streptozotocin (STZ) is known to...
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