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Genetic data provided by 21 autosomal STR loci from Chinese Tujia ethnic group |
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| Authors: | Guo-lian Yuan Chun-mei Shen Hong-dan Wang Wen-juan Liu Guang Yang Jiang-wei Yan Hai-Xia Qin Tong Xie Hangyan Ran Jie Yuan Zuochun Liu Bofeng Zhu |
| Institution: | 1. Scientific Research and Experiment Center, The Second Affiliated Hospital, School of Medicine, Xi’an Jiaotong University, Xi’an, 710004, People’s Republic of China 2. The Key Laboratory of Environment and Gene Related to Diseases (Xi’an Jiaotong University), Ministry of Education, Xi’an, 710061, People’s Republic of China 3. Blood Center of the Shaanxi Province, Shaanxi, 710061, People’s Republic of China 4. Medical Genetic Institute of Henan Province, People’s Hospital of Henan Province, Zhengzhou, 450003, People’s Republic of China 5. School of Medicine, Xi’an Jiaotong University, Xi’an, 710061, People’s Republic of China 6. Vascular Biology Center, Georgia Health Sciences University, Augusta, GA, 30912, USA 7. Beijing Institute of Genomics, Chinese Academy of Science, Beijing, 100029, People’s Republic of China 8. Department of Internal Medicine, Morehouse School of Medicine, Atlanta, GA, 30303, USA 9. School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510275, People’s Republic of China 10. Affiliated Hospital of Hubei Institute for Nationalities, Enshi, 445000, People’s Republic of China |
| Abstract: | The aim of this study was to investigate allelic frequency distribution and forensic genetic parameters of autosomal short tandem repeats (STR) loci of the population samples from 107 Tujia individuals from Chinese Hubei Province. Twenty-one autosomal STR genetic markers (D9S1122, D6S474, D6S1017, D5S2500, D4S2408, D3S4529, D2S441, D2S1776, D22S1045, D20S482, D1S1677, D1S1627, D1GATA113, D19S433, D18S853, D17S1301, D11S4463, D12ATA63, D10S1248, D10S1435 and D14S1434) were simultaneously amplified in a new multiplex polymerase chain reaction system. 155 alleles for all the STR loci from the Tujia population were observed and the corresponding allelic frequencies ranged from 0.005 to 0.589. Expected heterozygosity, polymorphic information content, power of discrimination and power of exclusion of the 21 STR loci in the Tujia population were from 0.579 to 0.824, from 0.525 to 0.802, from 0.773 to 0.945 and from 0.257 to 0.641, respectively. Our results indicate that the autosomal STRs multiplex system provides highly informative STR data and could be useful in forensic individual identification and parentage testing in this region. |
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