|
|||||
|
|
Novel single nucleotide polymorphism identification in interleukin-6 gene of Pakistani sheep |
|
| Authors: | Safdar Ali Masroor Ellahi Babar A Hossain Farid Pervez Akhtar Ali Raza Awan |
| Institution: | (1) Department of Animal Breeding and Genetics, University of Agriculture Faisalabad, Faisalabad, Pakistan;(2) Institute of Biochemistry & Biotechnology, University of Veterinary and Animal Sciences, Outfall Road, Civil Lines, Lahore, Pakistan;(3) Department of Agriculture and Animal Sciences, Nova Scotia Agricultural College, Truro, NS, Canada; |
| Abstract: | The present study aimed to identify single-nucleotide polymorphism (SNP) in coding and non-coding regions of interleukin-6 (IL-6) gene of Pakistani sheep. The IL-6 gene of 205 animals from nine sheep breeds were sequenced for screening of SNP. Characterizing the IL-6 gene revealed thirteen SNP sites within the intronic region of IL-6 gene. The novel SNPs found in the present study can serve as genetic marker for association studies with susceptibility/resistance to parasite infection in sheep. This is first report of SNP polymorphism of IL-6 gene of Pakistani sheep. |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |