| 新型抗肿瘤药DIDOX及其类似物的合成（Ⅱ） |
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| 引用本文： | 邵航,胡国荣.新型抗肿瘤药DIDOX及其类似物的合成（Ⅱ）[J].氨基酸和生物资源,1996,18(3):30-31. |
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| 作者姓名： | 邵航 胡国荣 |
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| 作者单位： | [1]山东师范大学 [2]山东省中医院 |
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| 摘 要： | 通过脂化、氨解等反应，合成了抗癌新药ＤＩＤＯＸ（３，４－二羟基苯并氧肟酸）及其三个类似物，并用ＩＲ证实了其结构特征［１～３］。
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| 关 键 词： | 抗肿瘤药物，DIDOX，合成，类似物 |
Synthesis of New Antineoplastic drug DIDOX And It's Analogues |
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| Shao Hong, Liu Chunxiang et al.Synthesis of New Antineoplastic drug DIDOX And It's Analogues[J].Amino Acids & Biotic Resources,1996,18(3):30-31. |
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| Authors: | Shao Hong Liu Chunxiang |
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| Institution: | ,Shao Hong, Liu Chunxiang et al(Department of Pharmacology Shandong Medical University. Jinan, 250012) |
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| Abstract: | The esterification of 3,4-dihydroxybenzoin acid with refluxing methanol and H_2SO_4 gives the corresponding methyl ester, which is then treated with hydroxylamine in water containing NaOH. |
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| Keywords: | Antineoplastic DIDOX Analogues Synthesis |
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