| 用高效液相色谱法(HPLC)测定肌苷中有关物质和降解产物 |
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| 引用本文： | 刘林,陈蔚江,李金屏.用高效液相色谱法(HPLC)测定肌苷中有关物质和降解产物[J].氨基酸和生物资源,2003,25(3):67-68. |
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| 作者姓名： | 刘林 陈蔚江 李金屏 |
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| 作者单位： | 湖北省药品检验所,湖北,武汉,430064 |
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| 摘 要： | 用HPLC测定肌苷中有关物质和降解产物 ,与主药有良好的分离效果。色谱柱为HypersilC1 8(2 5 0mm× 4 .6mm ,5 μm) ,流动相甲醇 -水 (甲醇与水体积比为 10∶90 ) ,流速 1mL·min- 1 ,检测波长 2 4 8nm。
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| 关 键 词： | 肌苷 高效液相色谱法 有关物质 |
| 文章编号： | 1006-8376(2003)03-0067-02 |
| 修稿时间： | 2003年5月15日 |
HPLC Determination of Related Compounds of Isonine |
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| LIU Lin,CHEN Wei-jiang,LI Jin-ping.HPLC Determination of Related Compounds of Isonine[J].Amino Acids & Biotic Resources,2003,25(3):67-68. |
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| Authors: | LIU Lin CHEN Wei-jiang LI Jin-ping |
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| Abstract: | Related compounds of isonine were determinated by HPLC .The analytical column was ODS C18(length:250mm×4.6mm;filler:Hypersil;size:5μm).The mobile phase consisted of methanol and water(10:90)and the flow rate was 1ml.min -1 . The detection was carried out with UV detector and the detection wavelength of 248nm was specified.The proposed method was selective,simple and accurate. |
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| Keywords: | related compounds isonine HPLC |
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