染色质重塑调控生物温度适应性的研究进展

温度是限制物种适应性分布的重要环境因子,对极端环境温度的耐受性决定生物分布和扩散范围,而表观遗传可以提供快速的响应机制,促使生物快速适应极端环境温度。染色质重塑作为表观遗传的重要组成部分之一,其可以通过调控胁迫相关基因的表达从而促进生物适应不良环境条件。本文主要阐述了染色质重塑复合物的分类、组成和染色质重塑的方式,梳理了染色质重塑在生物温度适应性中的研究进展,提出染色质重塑在生物适应不良环境温度过程中发挥重要作用,并对未来染色质重塑与温度适应性研究提出建议。

Research advance of chromatin remodeling in regulating biological temperature adaptability

Temperature is an important environmental factor that limits the distribution of species, and tolerance to extremely environmental temperatures determines the distribution and spread of organisms. Epigenetics can provide a rapid response mechanism that enables organisms to rapidly adapt to extreme ambient temperatures. Chromatin remodeling is an important epigenetic mechanism that can promote adaptation to adverse environmental conditions by regulating the expression of stress-related genes. Here, the classification and composition of chromatin remodeling complexes and the ways of chromatin remodeling were reviewed, as well as the research progress of chromatin remodeling in biological temperature adaptability were summarized. These findings indicate that chromatin remodeling plays an essential role in the process of biological adaptation to temperature stress. Moreover, we propose some suggestions for future studies on chromatin remodeling and temperature adaptation.