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PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc
Authors:Chin‐Chang Cheng  Yoshiyasu Uchiyama  Akihiko Hiyama  Sachin Gajghate  Irving M Shapiro  Makarand V Risbud
Institution:1. Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania;2. Department of Orthopaedic Surgery, Chang Gung Memorial Hospital at Chia‐yi, Graduate Institute of Clinical Medicine Science, Chang Gung University, Taoyuan, Taiwan;3. Department of Orthopaedic Surgery, Surgical Science, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa, Japan
Abstract:
Keywords:
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