| PIP3在中性粒细胞信号通路中的作用及生成调节 |
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| 引用本文： | 袁恒锋,刘倩倩,孟晓静.PIP3在中性粒细胞信号通路中的作用及生成调节[J].国外医学：分子生物学分册,2009(1):65-67. |
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| 作者姓名： | 袁恒锋 刘倩倩 孟晓静 |
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| 作者单位： | 南方医科大学公共卫生与热带医学学院职业卫生与职业医学系,广州市510515 |
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| 基金项目： | 国家自然科学基金（No.30800438）;本文得到蔡春青老师的支持和帮助,谨致谢! |
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| 摘 要： | 趋化性是中性粒细胞参与机体对抗病原体的一个基本的细胞反应。中性粒细胞的趋化过程中涉及一系列信号通路来调节其运动性和极性。信号分子磷酸酰肌醇三磷酸及其参与的信号通路在中性粒细胞趋化过程中起着重要的作用，其自身的生成也受到一系列复杂因素的调节。
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| 关 键 词： | 中性粒细胞 趋化信号通路 磷酸酰肌醇三磷酸 |
Effects and Generated Regulation of PIP3 in Neutrophil Signaling Pathway |
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| Authors: | YUAN Hengfeng LIU Qianqian MENG Xiaojing |
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| Institution: | (Department of Occupational Health and Occupational Medicine, Public Health and Tropical Medicine, Southern Medical University, Guangzhou, 510515, China) |
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| Abstract: | Chemotaxis is a basic cell response by which neutrophils fight against pathogens in the body. The neutrophil chemotactic process involves a series of signaling pathways to control its movement and polarity. The signaling molecule PIP3 and PIP3 involved signaling pathways play important roles in neutrophil chemotactic process, while the generation of PIP3 is regulated by a series of complex factors. |
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| Keywords: | neutrophil chemotaetic signaling pathway PIP3 |
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