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Fnr (EtrA) acts as a fine-tuning regulator of anaerobic metabolism in <Emphasis Type="Italic">Shewanella oneidensis</Emphasis>MR-1
Authors:Claribel Cruz-García  Alison E Murray  Jorge LM Rodrigues  Jeffrey A Gralnick  Lee Ann McCue  Margaret F Romine  Frank E Löffler  James M Tiedje
Institution:(1) Center for Microbial Ecology, Michigan State University, East Lansing, Michigan 48824-1325, USA;(2) Department of Crop and Soil Sciences, Michigan State University, East Lansing, Michigan 48824-1325, USA;(3) Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan 48824-1325, USA;(4) Department of Biology, University of Texas at Arlington, Arlington, Texas 76019, USA;(5) Department of Microbiology, University of Minnesota, St. Paul, MN 55108, USA;(6) Pacific Northwest National Laboratory, University of Tennessee, Richland, Washington 99352, USA;(7) Department of Microbiology, University of Tennessee, Knoxville, MN 37996, USA;(8) Department of Civil and Environmental Engineering, University of Tennessee, Knoxville, MN 37996, USA;(9) Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA;(10) Georgia Institute of Technology, School of Civil and Environmental Engineering, 311 Ferst Drive, Atlanta, GA 30332-0512, USA;(11) Division of Earth and Ecosystem Sciences, Desert Research Institute, Reno, NV 89512, USA
Abstract:

Background  

EtrA in Shewanella oneidensis MR-1, a model organism for study of adaptation to varied redox niches, shares 73.6% and 50.8% amino acid sequence identity with the oxygen-sensing regulators Fnr in E. coli and Anr in Pseudomonas aeruginosa, respectively; however, its regulatory role of anaerobic metabolism in Shewanella spp. is complex and not well understood.
Keywords:
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