| Institution: | (1) Department of Medical Microbiology and Immunology, University of Aarhus, Denmark;(2) LOKE Diagnostics ApS, Science Park Aarhus, Denmark;(3) Flanders Interuniversity Institute for Biotechnology, Department of Medical Protein Research, Ghent University, Belgium |
| Abstract: | Background Chlamydiae are obligate intracellular bacteria, which are important human pathogens. Genome sequences of C. trachomatis and C. pneumoniae have revealed the presence of a Chlamydia specific gene family encoding polymorphic outer membrane proteins, Pmps. In C. pneumoniae the family comprises twenty-one members, which are all transcribed. In the present study, the expression, processing and localisation of the sixteen full-length Pmps in C. pneumoniae strain CWL029 have been further investigated by two-dimensional gel electrophoresis and immunofluorescence microscopy. |
