Proteomics: Concepts and applications in human medicine |
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| Authors: | Safa Al-Amrani Zaaima Al-Jabri Adhari Al-Zaabi Jalila Alshekaili Murtadha Al-Khabori |
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| Institution: | Safa Al-Amrani, Zaaima Al-Jabri, Department of Microbiology and Immunology, Sultan Qaboos University, Muscat 123, OmanAdhari Al-Zaabi, Department of Human and Clinical Anatomy, Sultan Qaboos University, Muscat 123, OmanJalila Alshekaili, Department of Microbiology and Immunology, Sultan Qaboos University Hospital, Muscat 123, OmanMurtadha Al-Khabori, Department of Hematology, Sultan Qaboos University, Muscat 123, Oman |
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| Abstract: | Proteomics is the complete evaluation of the function and structure of proteins to understand an organism’s nature. Mass spectrometry is an essential tool that is used for profiling proteins in the cell. However, biomarker discovery remains the major challenge of proteomics because of their complexity and dynamicity. Therefore, combining the proteomics approach with genomics and bioinformatics will provide an understanding of the information of biological systems and their disease alteration. However, most studies have investigated a small part of the proteins in the blood. This review highlights the types of proteomics, the available proteomic techniques, and their applications in different research fields. |
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| Keywords: | Proteomics Biomarker Mass spectrometry Two-dimensional electrophoresis Drug discovery |
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| 点击此处可从《World journal of biological chemistry》浏览原始摘要信息 |
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