| 石墨烯及其衍生物氧化石墨烯作为新型药物载体材料在肿瘤治疗领域的应用研究 |
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| 引用本文： | 赵媛媛,殷婷婕,霍美蓉,周建平.石墨烯及其衍生物氧化石墨烯作为新型药物载体材料在肿瘤治疗领域的应用研究[J].微生物学杂志,2015(1). |
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| 作者姓名： | 赵媛媛 殷婷婕 霍美蓉 周建平 |
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| 作者单位： | 中国药科大学天然药物活性组分与药效国家重点实验室，江苏 南京 210009,中国药科大学天然药物活性组分与药效国家重点实验室，江苏 南京 210010,中国药科大学天然药物活性组分与药效国家重点实验室，江苏 南京 210011,中国药科大学天然药物活性组分与药效国家重点实验室，江苏 南京 210012 |
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| 基金项目： | 国家自然科学基金（No. 81102397）; 江苏省自然科学基
金（No. BK2012761）; 江苏省青蓝工程-中青年学术带头人培养项目（No.
02432009）; 中央高校基本科研业务费专项资金（No. JKPZ2013004）;
天然药物活性组分与药效国家重点实验室项目（No. JKGQ201107） |
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| 摘 要： | 石墨烯及其衍生物氧化石墨烯因具有水溶性好、比表面积大、载药量高以及易于修饰等优势，近年来在生物医药领域尤其在肿瘤治
疗领域的应用研究发展迅速。综述石墨烯及氧化石墨烯作为新型药物载体材料所具有的特性和生物安全性、表面修饰方式以及在肿瘤靶向
递药系统中的应用，为其在生物医药领域的应用研究提供新方法和新思路。
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| 关 键 词： | 石墨烯 氧化石墨烯 表面修饰 药物载体 肿瘤靶向递药 安全性 |
Research Advances in the Application of Graphene and Its Derivative, Graphene Oxide, as New Drug
Carrier Materials in the Field of Tumor Treatment |
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| ZHAO Yuanyuan,YIN Tingjie,HUO Meirong and ZHOU Jianping.Research Advances in the Application of Graphene and Its Derivative, Graphene Oxide, as New Drug
Carrier Materials in the Field of Tumor Treatment[J].Journal of Microbiology,2015(1). |
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| Authors: | ZHAO Yuanyuan YIN Tingjie HUO Meirong and ZHOU Jianping |
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| Institution: | State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China,State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210010, China,State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210011, China and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210012, China |
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| Abstract: | The application of graphene and its derivative, graphene oxide(GO), in bio-medical field, especially in the field of tumor treatment,
has been developed rapidly in recent years, owing to their good solubility in water, large specific surface area, high drug-loading capacity and easy
modification. The properties, biological safety and surface modification of graphene and GO as well as their application in tumor-targeted drug
delivery system as new drug carrier materials were reviewed so as to provide new method and new thinking for the research on their application in
bio-medical field |
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| Keywords: | graphene graphene oxide surface modification drug carrier tumor-targeted drug delivery safety |
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