白木香内生真菌抗肿瘤抗菌活性的筛选研究

白本香Aquilariasinensis（Lour．）Gilg]是我国特有的珍稀濒危药用植物。对已分离得到的白木香内生真菌的发酵液提取物的抗肿瘤抗菌活性进行了筛选。结果表明，对肿瘤细胞SF-268增殖的抑制率在90％以上的菌株有6株，占总菌株数的31．6％。其中有16株对金黄色葡萄球菌具有一定的抑菌活性，占总菌株教的84．2％，有9株表现较强的抑菌活性。另外有1株时白色念珠菌表现较强的抑菌活性；有2株对黑曲霉表现一定的抑菌活性。所有菌株对大肠埃希菌都没有表现明显的抑菌活性。

Screening of Antitumor and Antiseptic Activities of Endophytic Fungus from White Eaglewood (Aquilaria sinensis)

White eaglewood (Aquilaria sinensis) is a rare and endangered medicinal plant endemic of China. Endo-phytic fungi from the plant with antitumor and antiseptic activities in the extract of fermentation broth were screened. The results indicated that there were 6 strains exhibited inhibition against the proliferation of tumor cell SF-268 at the rate above 90%, account for 31.6% of total strains isolated; And another 16 strains possessed a certain bacterial in-hibition against Staphylococcus aureus, account for 84.2% of the total strains isolated, among them 9 strains had fairly strong inhibition against bacteria, one strain indicated fairly strong inhibition against Candida albicans, two strains showed a certain inhibition activity against AspergiUus niger. And all the strains isolated had not obvious inhibition ac-tivity against E. coli.